Vitamin B12: How vitamin B12 deficiency can affect adults dangerously | – Times of India

Vitamin B12 is an essential nutrient that is involved in numerous bodily functions. Vitamin B12, also known as cobalamin, plays a vital role in red blood cell formation, DNA synthesis, neurological health, and energy production.
However, despite being such an important nutrient, it is overlooked in diets. Adults mostly ignore adding the right amount of vitamin B12 to their food. It is crucial to note that lack of vitamin B12 in the body for a long time can cause severe and potentially irreversible consequences.
Vitamin B12 is a water-soluble vitamin primarily found in animal-based foods such as meat, fish, eggs, and dairy products. It is absorbed in the small intestine with the help of a protein called intrinsic factor, which is produced in the stomach. Once absorbed, B12 is involved in the formation and maturation of red blood cells, preventing anemia; maintains the myelin sheath, a protective coating around nerves, ensuring proper signal transmission; synthesis of DNA and energy metabolism.

How Vitamin B12 deficiency affects adults

If untreated for a longer time, vitamin B12 deficiency can have several impacts on the body ranging from dementia to neurological damage. It can cause chronic pain, balance issues, muscle weakness, and even paralysis in extreme cases. It can lead to brain atrophy, increasing the risk of dementia and Alzheimer’s disease. Studies suggest that even mild deficiencies can contribute to slower cognitive function and memory loss.
Lack of Vitamin B12 deficiency leads to abnormally large, immature red blood cells called megaloblasts which cause anemia. Less Vitamin B12 can increase homocysteine levels, an amino acid linked to a higher risk of heart disease and stroke. High homocysteine damages blood vessels and contributes to clot formation.
Chronic B12 deficiency can contribute to severe depression, anxiety, and psychosis. Correcting the deficiency often improves these symptoms significantly.

Is it only diet? Or what else can cause Vitamin B12 deficiency

Several factors can cause Vitamin B12 deficiency in adults. Apart from imbalance in diet, conditions like Crohn’s disease, celiac disease, or atrophic gastritis can affect the body’s ability to absorb Vitamin B12. Long-term use of antacids, proton pump inhibitors, or metformin can interfere with Vitamin B12 absorption.
Adults who are strictly vegetarians or vegans have a higher risk of getting vitamin B12 deficiency.

How to know if one has Vitamin B12 deficiency?

It is often difficult to diagnose Vitamin B12 deficiency. The symptoms can be subtle and mimic other conditions:
Vitamin B12 deficiency can affect the production of red blood production cells leading to fatigue and weakness.
Tingling, numbness, and “pins and needles” sensations, especially in the hands and feet, result from nerve damage caused by B12 deficiency.
Lack of vitamin B12 can lead to memory problems, difficulty concentrating, and even dementia-like symptoms. It can also lead to depression, irritability, and mood swings.
Inflammation of tongue, painful sores in the mouth and pale skin are seen when the body does not have enough vitamin B12.
Due to lack of vitamin B12, one also experiences heart palpitations and breathlessness.